Amber L Southwell
FACULTY & STAFF DIRECTORY
ADDITIONAL CONTACT INFORMATION
PublicationsReviews and Invited Reviews1 Review (Invited) Southwell AL, Patterson PH. Gene therapy in mouse models of huntington disease. Neuroscientist 17(2):153-62. (2011) PMID 21489966 2 Review (Invited) Southwell AL, Patterson PH. Antibody therapy in neurodegenerative disease. Rev Neurosci 21(4):273-87. (2010) PMID 21086760 Journal Articles1 Southwell AL, Bugg CW, Kaltenbach LS, Dunn D, Butland S, Weiss A, Paganetti P, Lo DC, Patterson PH. Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1. PLoS ONE 6(1):e16676. (2011) PMID 21304966 2 Southwell AL, Ko J, Patterson PH. Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease. J. Neurosci. 29(43):13589-602. (2009) PMID 19864571 3 Southwell AL, Khoshnan A, Dunn DE, Bugg CW, Lo DC, Patterson PH. Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. J. Neurosci. 28(36):9013-20. (2008) PMID 18768695 4 Chiu CS, Brickley S, Jensen K, Southwell A, Mckinney S, Cull-Candy S, Mody I, Lester HA. GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum. J. Neurosci. 25(12):3234-45. (2005) PMID 15788781 5 Zylka MJ, Dong X, Southwell AL, Anderson DJ. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc. Natl. Acad. Sci. U.S.A. 100(17):10043-8. (2003) PMID 12909716 6 Lopreato GF, Lu Y, Southwell A, Atkinson NS, Hillis DM, Wilcox TP, Zakon HH. Evolution and divergence of sodium channel genes in vertebrates. Proc. Natl. Acad. Sci. U.S.A. 98(13):7588-92. (2001) PMID 11416226
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